Isotonix OPC-3 Review

Isotonix OPC-3

Isotonix OPC-3

Isotonix OPC-3

Product Quality


Product Efficacy


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Value For Money



  • Powerful antioxidant that boosts the body's immune system
  • Maintains healthy cholesterol and blood glucose levels
  • Supports healthy skin and complexion
  • Contains Pycnogenol, a known compound that controls diabetes, relieve arthritis and protects the heart
  • Supplement is delivered in an isotonic solution to achieve maximum absorption by the body


  • Supplement is in powder form, which is less convenient to consume

Isotonix OPC-3 – The Potent Supplement For Antioxidant

By now, you might have heard of Isotonix OPC-3 as a powerful food supplement for antioxidant.  There are more benefits than just that.

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Isotonix OPC-3 Health Benefits

The key health benefits of consuming OPC-3 include:

a. Powerful antioxidant

Antioxidants are effective in preventing or delaying cell damage.

b. Promotes cardiovascular and joint health

c. Maintains healthy cholesterol and blood glucose levels. OPC-3 is ideal for adults with high cholesterol  and blood glucose levels, even for diabetics.

d. Supports blood vessel function

e. Supports healthy skin and complexion

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Why Isotonix OPC-3 plays an important role in your daily diet and nutrition?

Free radicals exist as unstable, highly reactive and uncharged molecules which are responsible for oxidation in our bodies. Because a free radical has an atomic structure with an unpaired electron, it basically scavenges the body for electrons and in the process, damages our cells, proteins and DNA, sometimes destroying them in the process.

Free radicals are naturally occurring and factors such as a stressful lifestyle, smoking, air pollution, environmental contaminants, exercising and natural aging all contribute to the creation of these harmful free radicals. Long-term oxidation due to free radicals can cause serious damage to our health. Though our bodies are self-healing, exposure to excessive  free radicals in the absence of antioxidants will affect our health gradually.

Antioxidants are natural cell protectors, as they neutralize free radicals, rendering them harmless. They come in the form of nutrients such as vitamins, minerals and enzymes. They work in 2 ways, namely in chain breaking and prevention. A chain breaking antioxidant basically stabilizes free radicals and render them harmless. Examples of such chain breaking antioxidants include Vitamin A, C and E. Preventive antioxidants prevents oxidation by scavenging free radicals.

Isotonix OPC-3 – Rich Source of Oligomeric Proanthocyanidins (OPCs)

Isotonix OPC-3 is a superior food suppplement, a rich source of antioxidants. It includes a potent combination of antioxidants such as bilberry, grape seed, red wine, pine bark extracts and citrus bioflavonoid complex. Oligomeric proanthocyanidins (OPCs) are bioflavonoids (complex organic plant compounds) found in fruits, vegetables and certain tree barks that offer high nutritional benefits to the human body.

Multiple studies have shown OPCs to be more powerful than vitamin C and vitamin E in neutralizing free radicals. Isotonix OPC-3 is the leading isotonic product to contain Pycnogenol in the world. Pycnogenol is a natural plant extract from the bark of the French maritime pine tree and is the most researched bioflavonoid till date.


Isotonix OPC-3 – Isotonic Solution Ensures Maximum Absorption By The Human Body

Isotonic, also known as isosmotic, means “same or equal osmotic pressure”. All fluids including, blood, plasma and tears in the body have a certain concentration called osmotic pressure. The body’s common osmotic pressure, which is isotonic, provides an environment for proper and consistent maintenance of body tissues. So for any substance to be absorbed easily and used in our body system, it must be delivered in an isotonic state. You might have noted that isotonic solutions are commonly used as intravenously infused fluids in hospitalized patients for this specific reason.

Not all dietary supplements are created the same even if their ingredients might bear similar resemblance. Unlike most supplements in the market, Isotonix dietary supplements are always delivered in an isotonic solution to achieve maximum absorption by the body. The isotonic solution allows nutrients to pass directly into the small intestine and absorbed quickly into the bloodstream, leaving little nutrition loss and achieving best results.

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Isotonix OPC-3 Featured In Worldwide News And Media Channels


Video Testimonials of Consumers Taking Isotonix OPC-3


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Key Ingredients of Isotonix OPC-3

Grape Seed Extract – Grape seed extract is typically extracted from the seeds of red grapes instead of white, which have a high concentration of compounds known as oligomeric proanthocyanidins (OPCs). Grape seed extract is a rich source of polyphenols, compounds with high antioxidant activity. Studies have shown that grape seed extract can help to maintain healthy cholesterol levels.

Red Wine Extract –  Red wine extract is another effective antioxidant. This extract is found in grape vines, roots, seeds and stalks. This extract maintains healthy blood circulation by strengthening capillaries, arteries and veins, and promoting overall cardiovascular health.

Pine Bark Extract – Pycnogenol is a natural plant extract from the bark of the maritime pine tree, which grows exclusively along the coast of southwest France in Les Landes de Gascogne. This natural forest environment is the unique source of pine bark. Pycnogenol is by far, one of the most researched ingredients in the natural-product marketplace. Published findings have demonstrated Pycnogenol’s wide array of beneficial effects on the human body. It acts as an antioxidant, and promotes the normal production of endothelial nitric oxide, which promotes the normal dilation of blood vessels.

Bilberry Extract – Bilberry extract is obtained from the leaves and berry-like fruit of a common European shrub closely related to the blueberry. Extracts of the ripe berries are known to contain flavonoid pigments known as anthocyanins, which are highly potent antioxidants. Scientific studies and research confirm that bilberry extract supports venous circulation. Bilberry extract helps maintain healthy circulation by strengthening capillaries, arteries and veins.

Citrus Bioflavonoid Complex – Bioflavonoids are antioxidants found in certain plants that act as light filters, which protect delicate DNA chains and other important macromolecules by absorbing ultraviolet radiation. They have been found to promote cardiovascular health, while helping to maintain healthy circulation by strengthening capillaries, arteries and veins.


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Frequently Asked Questions:

What is a bioflavonoid?

Bioflavonoids are complex organic plant compounds. Plants and fruits differ in colours based on the specific bioflavonoids they contain.

An increasing number of studies have shown how bioflavonoids support health. Bioflavonoids found in OPCs play a key role in maintaining vascular integrity and promoting cardiovascular health, ie protect the heart and blood vessels. Bioflavonoids have been shown to demonstrate support for healthy circulation and cell vitality.

How different is Isotonix OPC-3 from other bioflavonoid products in the market?

People often wonder what sets Isotonix OPC-3 apart from other similar products. Isotonix OPC-3 offers scientifically supported Oligomeric proanthocyanidins (OPCs). On top of their antioxidant properties, these individual OPCs have been shown to offer a myriad of specific health benefits. This science-driven selection of OPCs is unique to OPC-3, as is the Isotonix delivery system in an isotonic state, which enables quick and highly efficient absorption of the OPCs into the body system.

Why should everyone take Isotonix OPC-3?

Everyone is subject to free radical damage and oxidative stress. Free radicals develop as byproducts of physiological processes that occur within the body. This damage does not cause immediate noticeable harm at first, yet will accumulate over the years. This process is largely responsible for premature ageing, poor circulation, poor heart health and poor immunity.

OPCs are the most powerful natural free radical neutralizers. Daily, regular use is vital for keeping free radicals in check.

How should I take OPC-3?

OPC-3 is for ADULT USE ONLY. Children should not consume this supplement.

Pour one white bottle capful of powder into the overcap.  Add water to the line on the overcap (2 fl. oz or 60 ml) and stir. As a dietary supplement take once daily or as directed by your healthcare provider. Take two capfuls per 68-70 kg of body weight daily for the first 7-10 days, and take one capful thereafter as a maintenance programme.

Maximum absorption occurs when taken on an empty stomach. We wish to highlight that the product is isotonic only if the specified amounts of powder and water are used.

How long does it take to benefit from  Isotonix OPC-3?

Many effects of OPC-3 start to work after a single serving. OPC-3 not only provides some of the most potent and effective OPCs available, the unique Isotonix delivery system ensures that the small intestine rapidly absorbs the OPCs, which are available in the blood stream within minutes.

Taking Isotonix OPC-3 daily enables the body to sustain a consistent antioxidant defence against free radicals.

Can you take Isotonix OPC-3 in soda, juice, coffee, tea or other beverages, rather than water?

It is possible but not recommended. This product should only be taken as directed. In order to keep the product in an isotonic form and to achieve the maximum delivery speed, it needs to be taken on an empty stomach with 2 oz./ 60 ml of water per capful. Mixing the products with anything besides other Isotonix products and water slows down the delivery time and may affect the percentage of intake.

I am healthy and exercise regularly, so should I take  Isotonix OPC-3?

Everyone is vulnerable to the ageing process caused by continuous free radical damage. Athletes tend to be exposed to elevated levels of oxidative stress. Free radicals develop as byproducts during metabolism when calories are processed with oxygen. The increase in activity creates additional free radicals. In fact, these free radicals are known to limit performance, as free radicals appear to take their toll on muscle tissue.

Does OPC-3 have a rejuvenating effect?

The damage caused by free radicals accumulates with time. A cause for more worry is the fact that your body’s own defense mechanisms against  free radicals declines with increasing age – at a time when you need them the most. Suddenly, we find ourselves confronted with typical age-related problems. OPC-3 has the ability to clean and scavenge the free radicals that feast on cellular energy, and remove them from vital processes.

Does OPC-3 have visible benefits?

As OPCs support collagen production in the skin, an increase in skin smoothness and elasticity is the natural result. Skin smoothness was increased after three months as measured by 3-dimensional topography. It requires patience to show visible effects. It is essential to continuously take OPC-3 to keep skin cells at their peak vitality and health.

On a short-term basis, many people notice a fresher-looking and hydrated skin complexion. This is a result of healthy blood microcirculation, which helps detoxify the skin and improves the nutrient supply.

What are the cardiovascular health benefits of OPCs?

Scientist Albert Szent-Györgyi, who received the Nobel Prize for the discovery of vitamin C, was the one who made the discovery of OPCs. Szent-Györgyi found that OPCs work in a similar fashion as vitamin C in  strengthening the walls of arteries, veins and capillaries.

Over the last 20 years, scientists discovered that OPCs provide a lot of benefits for the cardiovascular system. Epidemiological studies have shown that regular intake of OPC antioxidants supports a healthy cardiovascular system. OPCs are also particularly helpful in maintaining healthy cholesterol levels and healthy arteries.

What exactly is Pycnogenol?

Pycnogenol in Isotonix OPC-3 plays a key role, as it promotes healthy nitric oxide (NO) levels. Pycnogenol is the trademark of Horphag Research (UK) Ltd. for a standardized extract of bark of the French maritime pine tree. Pycnogenol is renowned for its extensive clinical research with more than 120 studies published in peer-reviewed medical journals. NO is a tiny molecule that promotes relaxation of arteries and supports normal artery diameter and blood flow. Healthy nitric oxide NO levels also maintains normal blood pressure. This benefit has been explicitly demonstrated with Pycnogenol in studies. Nitric oxide also promotes healthy blood platelet activity and promotes a normal, fluid environment in our body and thereby promotes  cardiovascular health.

Does Isotonix OPC-3 contain pork, lard or pork products?


Is Isotonix OPC-3 vegetarian?


Is this product safe for consumption and manufactured in a Good Manufacturing Practice(GMP) facility?

Yes, this product is safe for consumption and manufactured in a GMP compliant facility which is inspected by the Food and Drug Administration (FDA) of the United States of America.


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(Isotonix OPC-3 is available for shipping to different countries. To check if your location is included, click on the product image or check out button and scroll to the top of the product page and select your country and language.)

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About the Author

Haley Nichols
Haley Nichols
Haley Nichols is an advocate of healthy lifestyle, writer and researcher. Active in the health and medical industry, she has been helping many people, both ill and normal folks set their health right with her health and nutrition tips.